吴红苗
(茂名石化医院,广东 茂名,525011)
中图分类号:R735.2 文献标识码:A 文章编号:1674-7860(2016)15-0136-02 证型:IDGB
【摘 要】目的:观察养胃消瘀汤治疗慢性萎缩性胃炎癌前病变的疗效及HP相关性。方法:选取我院2013年1月—2015年6月就诊慢性萎缩性胃炎癌前病变患者34例。病例分组方法:数字抽签法,随机分为对照组和治疗组。对照组给予胃复春片;治疗组给予养胃消瘀汤。比较指标:①总有效率;HP转阴率;②治疗前后患者胃液游离酸、PH、蛋白酶的差异。结果:跟对照组比较,①治疗组总有效率、HP转阴率更高,x2检验P<0.05,有统计学意义;②治疗组胃液游离酸、PH、蛋白酶改善更佳,t检验P<0.05,有统计学意义。结论:养胃消瘀汤治疗慢性萎缩性胃炎癌前病变的疗效确切,有助于提高HP根除率,改善患者胃液情况,值得推广。
【关键词】养胃消瘀汤;慢性萎缩性胃炎癌前病变;疗效;HP
【Abstract】Objective: To observe the clinical effect of Yangwei Xiaoyu Decoction in treatingprecancerous lesions of chronic atrophic gastritis and HP correlation. Methods:Research objects: 34cases of precancerous lesions of chronic atrophic gastritis patients who wereadmitted to our hospital from January 2013 to June 2015. Case grouping method:digital drawing method. 34 patients were divided into the treatment group andthe control group. The control group was given Weifuchun tablets; the treatmentgroup was given Yangwei Xiaoyu Decoction. Indicators:① the total efficiency;HP negative rate;② the difference of free acid, pH and protease before andafter treatment in gastric juice. Results:Compared with the control group, ①in the treatment group, the total efficiency and HPnegative rate were higher, P<0.05 by x2test, the difference was of statistical significance; ②the improvement of freeacid, pH and protease in gastric juice of the treatment group was better, P<0.05 by t test, the difference was ofstatistical significance. Conclusion:Yangwei Xiaoyu Decoction had significant effect in treatingprecancerous lesions of chronic atrophic gastritis and it helped to improve theHP eradication rate, promote the situation of patients with gastric juice andwas worthy of being popularized.
【Keywords】Yangwei XiaoyuDecoction; Precancerous lesions of chronic atrophic gastritis; Efficacy; HP
doi:10.3969/j.issn.1674-7860.2016.15.066
参考文献:
[1]史佳宁,郝微微.慢性萎缩性胃炎癌前病变基因与中医证型相关性研究进展[J].南京中医药大学学报,2015,22(2):194-196.
[2]姚学渊.养胃理气行瘀法治疗慢性萎缩性胃炎癌前病变40例[J].江苏中医药,2013,14(9):45-45.
[3]相宏杰,王惠娟,曹志群,等.芪莲舒痞方对CAG大鼠胃黏膜血流量及病理形态影响的实验研究[J].世界中西医结合杂志,2013,8(2):181-183
[4]白宇宁,王少丽,姚乃礼,等.健脾通络解毒方加减辨治慢性萎缩性胃炎癌前病变40例临床观察[J].中医杂志,2014,55(4):301-304.
[5]潘如燕.两种基因蛋白在慢性萎缩性胃炎不同中医证型中的表达[J].时珍国医国药,2013,24(3):729-730.
[6]张露,沈洪,周晓波,等.从气虚血瘀论治慢性萎缩性胃炎癌前病变[J].北京中医药大学学报(中医临床版),2013,20(1):16-20.
[7]付航,刘喜平,李沛清,等.敦煌平胃丸治疗慢性萎缩性胃炎癌前病变48例[J].中医研究,2015,28(1):20-22.
[8]卢晓杰,焦守霞,李建民,等.慢性萎缩性胃炎癌前病变胃黏膜病理变化与中医证型及幽门螺杆菌感染的相关性研究[J].现代中西医结合杂志,2015,21(26):2910-2912.